Peroxisome Proliferator–Activated Receptors as Transcriptional Nodal Points and Therapeutic Targets
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چکیده
منابع مشابه
Peroxisome proliferator-activated receptors as transcriptional nodal points and therapeutic targets.
Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors involved in the transcriptional regulation of key metabolic pathways such as lipid metabolism, adipogenesis, and insulin sensitivity. More recent work implicates all 3 PPAR isotypes (alpha, gamma, and delta, also known as beta or beta/delta) in inflammatory and atherosclerotic pathways. Because these ...
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ژورنال
عنوان ژورنال: Circulation
سال: 2007
ISSN: 0009-7322,1524-4539
DOI: 10.1161/circulationaha.104.475673